Curiously, the physical environment within the home setting has not been extensively studied in relation to older adults' physical activity and sedentary behaviors. immune thrombocytopenia In light of the fact that older people increasingly spend substantial amounts of time in their homes, the importance of optimizing their living spaces for healthy aging is evident. This study, therefore, is set to explore how older adults view the modification of their domestic spaces to stimulate physical activity, leading to healthy aging outcomes.
This formative research study will implement a qualitative, exploratory design, characterized by in-depth interviews and a strategically chosen sample. Employing IDIs will enable the collection of data from the study participants. This formative research in Swansea, Bridgend, and Neath Port Talbot necessitates a formal request by senior citizens from various community groups to recruit participants via existing connections. The study's data will be analyzed thematically using NVivo V.12 Plus software as a tool.
The Swansea University College of Engineering Research Ethics Committee (NM 31-03-22) has approved the ethical aspects of this research undertaking. Dissemination of the study's findings will encompass both the scientific community and the study participants. The results will empower us to delve into the viewpoints and beliefs of older adults concerning physical activity within the context of their home surroundings.
The Swansea University College of Engineering Research Ethics Committee (NM 31-03-22) has bestowed ethical approval upon this study. Dissemination of the study's findings will occur among the scientific community and the study participants. The findings will allow us to delve into how older adults view and feel about physical activity within the confines of their homes.
Evaluating the suitability and safety of neuromuscular stimulation (NMES) as a supplemental approach to rehabilitation programs for patients undergoing vascular and general surgical procedures.
A randomized controlled trial, single-center, prospective, single-blind, and parallel-group in design. This UK secondary care study, a single-centre investigation, will take place at a National Healthcare Service Hospital. Surgical patients, either vascular or general, 18 years or older, are included if their Rockwood Frailty Score is 3 or above upon admission. The exclusionary reasons for not participating in the trial encompass the presence of implanted electrical devices, pregnancy, acute deep vein thrombosis, and an inability or unwillingness to participate. One hundred is the anticipated number of recruits. In preparation for surgery, participants will be randomly assigned to either the active NMES group, labeled Group A, or the placebo NMES group, designated as Group B. Participants, kept unaware of treatment specifics, will employ the NMES device one to six times daily (30 minutes per session) post-surgery, complemented by standard NHS rehabilitation, until their discharge. The acceptability and safety of NMES are determined by the evaluation of the device satisfaction questionnaires at discharge and the adverse events that occurred during the hospital stay. Activity tests, mobility and independence measures, and questionnaires were used to evaluate the secondary outcomes of postoperative recovery and cost-effectiveness, compared across the two groups.
Ethical review and approval were secured from the London-Harrow Research Ethics Committee (REC) and the Health Research Authority (HRA), specifically under reference 21/PR/0250. National and international conferences, coupled with peer-reviewed journal publications, will serve as platforms for presenting the findings.
The clinical trial identified by NCT04784962.
Data relating to the clinical trial NCT04784962 are available.
Nursing and personal care staff are empowered by the EDDIE+ program, a multi-faceted intervention rooted in sound theoretical principles, to identify and effectively manage the early warning signs of decline in aged care residents. By means of intervention, the objective is to decrease the number of unneeded hospitalizations arising from residential aged care homes. A stepped wedge randomized controlled trial will be accompanied by an embedded process evaluation aimed at determining the fidelity, acceptability, mechanisms of action, and contextual barriers and enablers inherent in the EDDIE+ intervention.
The research team is currently studying twelve RAC homes in Queensland, Australia. Guided by the i-PARIHS framework, a mixed-methods evaluation will analyze the fidelity of the intervention, the contextual obstacles and supports, the mechanisms driving its impact, and the program's acceptability from various stakeholder viewpoints. The collection of quantitative data will be prospective, drawing on project documentation for baseline contextual mapping of participating sites, documented activity, and regularly scheduled check-in communications. Using semi-structured interviews with a spectrum of stakeholder groups, qualitative data will be obtained after the intervention. The i-PARIHS conceptual model, including innovation, recipients, context, and facilitation, will be the guiding principle for analyzing the quantitative and qualitative data collected.
The Bolton Clarke Human Research Ethics Committee (approval number 170031) has granted ethical approval for this study, supplemented by administrative ethical approval from the Queensland University of Technology University Human Research Ethics Committee (2000000618). Full ethical approval mandates a waiver of consent for access to anonymized resident data, comprising demographics, clinical records, and healthcare utilization information. To achieve a separate data linkage between health services and RAC home addresses, a Public Health Act application will be filed. The research findings will be spread through a range of channels, specifically journal publications, conference presentations, and stakeholder-focused interactive webinars.
The Australia New Zealand Clinical Trial Registry (ACTRN12620000507987) ensures transparency and accountability in the conduct of clinical trials.
Clinical trial data is meticulously maintained within the Australia New Zealand Clinical Trial Registry, specifically identified by ACTRN12620000507987.
Iron and folic acid (IFA) supplementation, despite its ability to improve anemia in pregnant women, demonstrates a less than desirable adoption rate in Nepal. Our hypothesis was that providing virtual counseling twice during mid-pregnancy would improve adherence to IFA tablets during the COVID-19 pandemic, compared to antenatal care alone.
This non-blinded, individually randomized controlled trial in the plains of Nepal is evaluating two treatment groups: (1) standard antenatal care; and (2) standard antenatal care supplemented by virtual antenatal counseling. Pregnant women between the ages of 13 and 49, married and capable of answering questions, whose pregnancy is in the 12-28 week range, and who intend to reside in Nepal for the upcoming five weeks are eligible for enrollment. The intervention's structure includes two virtual counseling sessions, delivered by auxiliary nurse-midwives, separated by at least two weeks, during the mid-pregnancy period. A dialogical problem-solving approach, central to virtual counselling, assists pregnant women and their families. Orthopedic oncology Randomization procedures were used to assign 150 pregnant women to each arm, taking into account prior pregnancy experience (primigravida or multigravida) and baseline iron-fortified food consumption. An 80% power calculation was applied to identify a 15% absolute difference in the primary outcome, assuming a 67% prevalence in the control group, accounting for a 10% anticipated loss to follow-up. Enrollment is followed by the measurement of outcomes 49 to 70 days later or, in the case of earlier delivery, immediately upon delivery.
Over the last 14 days, the consumption of IFA occurred on at least 80% of those days.
Dietary variety, the consumption of intervention-backed foods, and strategies for improving iron absorption, along with an understanding of foods high in iron, are all crucial aspects of nutrition. Examining acceptability, fidelity, feasibility, coverage (equity and reach), sustainability and pathways to impact forms the core of our mixed-methods process evaluation. We determine the monetary value and cost-effectiveness of the intervention, observed from a provider's perspective. Primary analysis, leveraging logistic regression, proceeds with an intention-to-treat design.
We secured ethical approval from both the Nepal Health Research Council (570/2021) and the UCL ethics committee (14301/001). Peer-reviewed journal articles and engagement with policymakers in Nepal will serve as channels for disseminating our findings.
The ISRCTN registration number, 17842200, denotes this research trial's identification within the registry.
A research project, bearing the unique identification code ISRCTN17842200, has been recorded.
The discharge of frail older adults from emergency departments (EDs) to their homes is fraught with unique obstacles stemming from interconnected physical and social issues. find more By incorporating in-home assessments and interventions, paramedic supportive discharge services assist in resolving these difficulties. We seek to characterize existing paramedic programs whose primary function is to support patient discharge from an emergency department or hospital, thus avoiding redundant hospital admissions. A detailed mapping of the literature surrounding paramedic supportive discharge services will outline (1) the necessity of such programs, (2) the target populations, referral networks, and service providers, and (3) the assessments and interventions offered.
Our research will include studies on the broader responsibilities of paramedics, specifically focusing on community paramedicine, and on the expanded post-discharge care available from hospital emergency departments or the hospital. No restrictions will be placed on the language of any study design included in the analysis. Between January 2000 and June 2022, we will include in our study peer-reviewed articles, preprints, and a targeted search of grey literature resources. The scoping review, which is proposed, will be carried out in strict adherence to the Joanna Briggs Institute's methodology.